COMPANY
About
We’re developing AI that learns across biological systems, with applications in medicine, biological engineering, and biosecurity.
RADICAL NUMERICS
Our Story

01
Origins
We came together through a series of unconventional technical bets, from long-context architectures with Hyena to modeling and generating DNA with Evo and Evo 2. When existing approaches fell short, we built new architectures and systems. We started Radical Numerics to take that work further.
02
What We’re Building
We’re building toward general biological intelligence. Our model, Omnii, learns across DNA, RNA, proteins, and other biological signals to read, write, and interpret biology: predict biological effects, generate sequences, and identify relationships that guide research.
Biology is a whole-system problem. Our thesis is that learning these signals together provides the context needed for better predictions, stronger candidate designs, and insights unavailable from any one signal alone.
03
Our Mission
Our mission is to solve biology. We want to help people prevent and treat disease, create new biological functions, and expand what can be engineered with biology.
We measure progress through scientific evaluation and experimental results. Ultimately, success means lives saved, diseases cured, and new biological capabilities made possible.
04
Our Dual Mandate
We built Radical Numerics to advance biological intelligence and strengthen biosecurity together. The capabilities that enable new medicines and biological designs can also be misused. Our research pursues both the ability to engineer biology and the ability to identify and respond to biological threats.
Research Trajectory
[01]
Hyena Long-Context Modeling
Architectures for extreme sequence lengths.
[02]
Evo
Generative genomics.
[03]
Evo 2
Scaling biological foundation models.
[04]
Omnii-1
Multimodal Genome Language Model.
TEAM
Founders

Eric Nguyen
Co-Founder & CEO
AI researcher working across biological intelligence, multimodal learning, computer vision, and AI-assisted healthcare. Eric started the Evo project during his PhD in Bioengineering and AI from Stanford and previously worked with Google DeepMind's Co-Scientist team and Google Research.

Michael Poli
Co-Founder & Chief AI Scientist
Michael’s research covers model architectures and efficient AI systems for pretraining and inference. At Stanford, he co-developed the Hyena family of architectures and led pretraining for the Evo models. He was later a senior member of technical staff at Together AI and a founding scientist at Liquid AI.

Stefano Massaroli
Co-Founder & President
Researcher working across deep learning theory, numerical linear algebra, signal processing, dynamical systems, and optimal control. Stefano has held research positions at RIKEN and Mila and was a founding scientist at Liquid AI.

Armin W Thomas
Co-Founder & CTO
Armin’s research spans pretraining, model architectures, and AI for science. At Stanford, he co-developed the genome language models Evo and HyenaDNA. He later worked on automated architecture design as a senior researcher at Liquid AI.
ADVISORS
Advised Across AI, Biology, and Biosecurity.
01
George Church
Professor of Genetics, Harvard Medical School
02
Tri Dao
Co-founder & Chief Scientist, Together AI
03
Paul Friedrichs
Major General (Ret), Former Command Surgeon of Air Combat Command
04
Eric Horvitz
Chief Scientific Officer, Microsoft
05
Jill Hruby
Former Head of Sandia National Labs
06
Chris Ré
Professor of Computer Science, Stanford University
07
Ben Spector
CEO, Flapping Airplanes
08
Andrew Weber
Senior Fellow, Council on Strategic Risks